Conventional e-Business models using the Client/Server architecture has always been complex, thorny and expensive. The quantity and assortment of hardware, software and middleware technologies used in order to run them was intimidating. With the emergence of Cloud computing, the technologies needed for an e-Businesses application are managed by experienced third parties who offer servers, storage management, network technologies, and virtualization technologies. This manuscr ipt presents the accomplishment of the job scheduling algorithm developed for an emblematic e-Business model using GI/G/3/n/k queuing theory perception. Finally, the associated simulations and numeral results are provided, to assurance the Quality of Service (QoS) for all throughput of system.