本文给出了一种混合多级式多聚焦图像融合方法。对于三层小波分解的多聚焦图像融合，每幅图像被分解为三层十个频带。对这十个频带本文分别采用三种方法进行融合。对于低频系数，本文仍然采用求平均法；对于高频系数本文采用方差法和最大系数法进行融合。它们的计算量比最大系数法大一些，但是融合结果更接近于原始清晰图像，而相比于方差法，它们的计算量小的多，但是融合质量稍差一些，应用者可以根据不同的需要进行选择。-This paper presents a hybrid multi-level multi-focus image fusion method. For the three wavelet decomposition of multi-focus image fusion, each image is divided into three ten-band. In this paper, these ten bands using three methods of integration. For low-frequency coefficients, the paper still uses the averaging method　this paper for high-frequency coefficients of variance and maximum coefficient method integration. They calculated the maximum coefficient larger than, but closer to the original fused a clear picture, but compared to the variance method, they calculated the amount of smaller, lower quality, but some of the integration, according to different application needs can selection.